Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques
نویسندگان
چکیده
منابع مشابه
Cerebral amyloid angiopathy.
Brain of a 66 year old woman with a four year history of progressive dementia with episodes of encephalopathy. Opposite: Multiple small, cystic, and occasionally confluent cortical scars (arrows) were restricted to the cerebrum and were due to cerebral amyloid angiopathy. Histological examination of the cortex in the postmortem brain showed numerous neuritic plaques and neurofibrillary tangles ...
متن کاملCerebral amyloid angiopathy
Cerebral amyloid angiopathy is increasingly recognized as a major cause of hemorrhagic stroke in the elderly as well as an important contributor to the growing challenge of vascular cognitive impairment, even in cerebral amyloid angiopathy patients without hemorrhagic stroke. Among the advances highlighted in this update are: (1) the importance of sulcal bleeding events in early recurrent hemor...
متن کاملCerebral amyloid angiopathy.
To cite: Sharma N, Vyas S. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-201558 DESCRIPTION A 72-year-old man presented with headache, vomiting and diminution of vision. There was no history of smoking, diabetes mellitus, hypertension or use of aspirin or recreational drugs. The general physical examination, pulse, blood pressure, chest and cardiovascular ...
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Background and Purpose: Microaneurysms and fibrinoid necrosis of cerebral cortical arteries have been reported to be related to the pathogenesis of intracerebral hemorrhage associated with cerebral amyloid angiopathy. To elucidate the pathogenesis of such vascular lesions, we conducted the present study. Methods: Five hundred serial sections from brain tissue of a patient with severe amyloid an...
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Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved. Of these, sporadic amyloid β-protein (Aβ)-type CAA is most commonly found in older individuals and in patients with Alzheimer's disease (AD). Cerebrovascular Aβ deposits accompany functional and pathological changes in cerebral blood vesse...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2008
ISSN: 1601-1848
DOI: 10.1111/j.1601-183x.2007.00380.x